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Research focus and Research collaborations


Research focus

Pharmacokinetics of biological treatments:
Ron Mathot, Krisztina Gecse, Mark Löwenberg, Geert DHaens

Fecal microbiota transplantation for ulcerative colitis:
Cyriel Ponsioen, Geert D’Haens

Cell type characterization in fistulas in Crohn’s disease:
Christianne Buskens, Manon Wildenberg, Andre Li Yim, Wouter de Jonge, Krisztina Gecse, Geert D’Haens, Willem Bemelman, Cyriel Ponsioen, Peter Henneman

Advanced imaging of fibrostenotic and fistulizing Crohn’s disease:
Jaap Stoker, Mark Löwenberg, Krisztina Gecse, Guus van Dongen, Geert D’Haens, Christianne Buskens

Biomarkers for Tyk-2 inhibition in ulcerative colitis (collaboration BMS):
Wouter de Jonge, Geert D’Haens, Andrew Yi Lim, Peter Henneman
Primary Sclerosing Cholangitis:
Cyriel Ponsioen

Hyperbaric oxygen for fistula treatment:
Nina Lansdorp, Krisztina Gecse, Christianne Buskens, Geert D’Haens, Rob van Hulst
Ileocecal resection with and without mesentery (SPICY trial):
Christianne Buskens, Willem Bemelman

Prevention of postoperative recurrence of Crohn’s disease with vedolizumab (collaboration TAKEDA):
Geert D’Haens, Krisztina Gecse
Pouch inflammation and dysfunction:
Willem Bemelman, Roel Hompes

Biomarkers for treatment response with tofacitinib in ulcerative colitis:
Sara van Gennep, Geert D’Haens, Aart Mookhoek, Evgeni Levin

Epigenetic prediction of treatment response to biologics in Crohn’s disease (collaboration University of Oxford):
Andrew Yi Lim, Vincent Joustra, Mark Löwenberg, Peter Henneman, Wouter de Jonge, Isthu Hageman, Geert D’Haens

Ultrasound assessment of inflammatory bowel disease:
Krisztina Gecse, Floris de Voogd, Maria de Jonge

Dysplasia in longstanding colitis:
Charlotte Peters, Joep Grootjans, Evelien Dekker, Geert D’Haens

Defining ‘normal life’ in IBD (collaboration Eli Lilly):
Joep van Oostrom, Krisztina Gecse, Geert D’Haens

Crohn’s disease exclusion diet for mucosal healing: Paradise trial (collaboration Paris and Tel Aviv):
Geert D’Haens

Treatment optimization and topical delivery of thiopurines:
Nanne de Boer

Purinethol treatment for ulcerative colitis: OPTIC trial:
Mark Löwenberg, Geert D’Haens, Adriaan Volkers, Nanne de Boer

Video Capsule Assessment of Crohn’s disease (collaboration MEDTRONIC):
Mark Löwenberg, Adriaan Volkers, Geert D’Haens
Early versus late introduction of vedolizumab for Crohn’s and ulcerative colitis (Love-UC and

Love-CD)(collaboration Takeda):
all clinicians
Safe withdrawal of antiTNF treatment for Crohn’s disease- CEASE trial (collaboration Erasmus Rotterdam):
Djuna de Jong, Geert D’Haens

Methotrexate pK:
Gerd Bouma

Charlotte Peters and Nanne de Boer

Research collaborations

  • Helmsley Charitable Trust
  • Amsterdam Imaging Centre
  • Horaizon
  • Oxford IBD Centre
  • Sanquin Research Institute
  • Procise Diagnostics